Investigational New Drug Application

/ˌɪnvɛstəˈɡeɪʃənl nuː drʌɡ ˌæplɪˈkeɪʃən/

Definitions

  1. (n.) A regulatory submission to the FDA seeking permission to start clinical trials of a new drug in humans.
    The pharmaceutical company filed an investigational new drug application before beginning clinical trials.

Forms

  • investigational new drug application
  • investigational new drug applications

Commentary

The term is strictly used in U.S. FDA regulatory context to denote the preclinical to clinical trial transition approval; precise drafting avoids conflation with marketing approvals.

This glossary is for general informational and educational purposes only. Definitions are jurisdiction-agnostic but reflect terminology and concepts primarily drawn from English and American legal traditions. Nothing herein constitutes legal advice or creates a lawyer-client relationship. Users should consult qualified counsel for advice on specific matters or jurisdictions.

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